What p-values actually mean:
What they're commonly taken to mean?
That is, p-values measure Pr(observations | null hypothesis) whereas what you want is more like Pr(alternative hypothesis | observations).
(Actually, what you want is more like a probability distribution for the size of the effect -- that's the "overly binary* thing -- but never mind that for now.)
So what are the relevant differences between these?
If your null hypothesis and alternative hypothesis are one another's negations (as they're supposed to be) then you're looking at the relationship between Pr(A|B) and Pr(B|A). These are famously related by Bayes' theorem, but they are certainly not the same thing. We have Pr(A|B) = Pr(A&B)/Pr(B) and Pr(B|A) = Pr(A&B)/Pr(A) so the ratio between the two is the ratio of probabilities of A and B. So, e.g., suppose you are interested in ESP and you do a study on precognition or something whose result has a p-value of 0.05. If your priors are like mine, your estimate of Pr(precognition) will still be extremely small because precognition is (in advance of the experimental evidence) much more unlikely than just randomly getting however many correct guesses it takes to get a p-value of 0.05.
In practice, the null hypothesis is usually something like "X =Y" or "X<=Y". Then your alternative is "X /= Y" or "X > Y". But in practice what you actually care about is that X and Y are substantially unequal, or X is substantially bigger than Y, and that's probably the alternative you actually have in mind even if you're doing statistical tests that just accept or reject the null hypothesis. So a small p-value may come from a very carefully measured difference that's too small to care about. E.g., suppose that before you do your precognition study you think (for whatever reason) that precog is about as likely to be real as not. Then after the study results come in, you should in fact think it's probably real. But if you then think "aha, time to book my flight to Las Vegas" you may be making a terrible mistake even if you're right about precognition being real. Because maybe your study looked at someone predicting a million die rolls and they got 500 more right than you'd expect by chance; that would be very exciting scientifically but probably useless for casino gambling because it's not enough to outweigh the house's advantage.
[EDITED to fix a typo and clarify a bit.]
Thank you - I get it now.
Frequentist statistics is a wide field, but in practice by innumerable psychologists, biologists, economists etc, frequentism tends to be a particular style called “Null Hypothesis Significance Testing” (NHST) descended from R.A. Fisher (as opposed to eg. Neyman-Pearson) which is focused on
NHST became nearly universal between the 1940s & 1960s (see Gigerenzer 2004, pg18), and has been heavily criticized for as long. Frequentists criticize it for:
What’s wrong with NHST? Well, among other things, it does not tell us what we want to know, and we so much want to know what we want to know that, out of desperation, we nevertheless believe that it does! What we want to know is, “Given these data, what is the probability that H0 is true?” But as most of us know, what it tells us is “Given that H0 is true, what is the probability of these (or more extreme) data?” These are not the same…
Similarly, the cargo-culting encourages misuse of two-tailed tests, avoidance of multiple correction, data dredging, and in general, “p-value hacking”.
(An example from my personal experience of the cost of ignoring effect size and confidence intervals: p-values cannot (easily) be used to compile a meta-analysis (pooling of multiple studies); hence, studies often do not include the necessary information about means, standard deviations, or effect sizes & confidence intervals which one could use directly. So authors must be contacted, and they may refuse to provide the information or they may no longer be available; both have happened to me in trying to do my dual n-back & iodine meta-analyses.)
Critics’ explanations for why a flawed paradigm is still so popular focus on the ease of use and its weakness; from Gigerenzer 2004:
Shifts away from NHST have happened in some fields. Medical testing seems to have made such a shift (I suspect due to the rise of meta-analysis):
0.1 Further reading
More on these topics:
The perils of NHST, and the merits of Bayesian data analysis, have been expounded with increasing force in recent years (e.g., W. Edwards, Lindman, & Savage, 1963; Kruschke, 2010b, 2010a, 2011c; Lee & Wagenmakers, 2005; Wagenmakers, 2007).
Although the primary emphasis in psychology is to publish results on the basis of NHST (Cumming et al., 2007; Rosenthal, 1979), the use of NHST has long been controversial. Numerous researchers have argued that reliance on NHST is counterproductive, due in large part because p values fail to convey such useful information as effect size and likelihood of replication (Clark, 1963; Cumming, 2008; Killeen, 2005; Kline, 2009 [Becoming a behavioral science researcher: A guide to producing research that matters]; Rozeboom, 1960). Indeed, some have argued that NHST has severely impeded scientific progress (Cohen, 1994; Schmidt, 1996) and has confused interpretations of clinical trials (Cicchetti et al., 2011; Ocana & Tannock, 2011). Some researchers have stated that it is important to use multiple, converging tests alongside NHST, including effect sizes and confidence intervals (Hubbard & Lindsay, 2008; Schmidt, 1996). Others still have called for NHST to be completely abandoned (e.g., Carver, 1978).
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