A prominent pop-culture example is the Mass Effect sci-fi game series. Unless Commander Shepard's gender is directly relevant (such as during romantic subplots), he/she will say the exact same lines whether man or woman.

Over five years and three lengthy and ambitious games, I've probably read hundreds of pages of people discussing every aspect of the series and its narrative. The single time I can remember anyone saying that 'FemShep' felt a bit off was in direct response to the above observation; outside of that, she was wildly popular and often named as a positive model for the writing of female protagonists.