Seconding this request. I would say the basic argument is similar to arguments against theft as a generalized policy eg it disincentivizes creation and hard work. Generalized violence disincentivizes civilization if you look at civilization as a framework for the interaction of strangers in large groups or individually but interchangeably. Basically, a culture of violence devolves to groups of people that can only trust very small numbers of other people on the level of family or tribe. The idea that you can venture into town to purchase anything you want and not have to worry about being murdered by a stranger is extremely important, in my view.
The man-made object responsible for the most deaths worldwide is the tobacco cigarette. It isn't even close.
Tobacco kills 443,000 Americans a year and 5 million people a year worldwide. This is more than the total number of people killed by cars and firearms combined. Cars kill about 32,000 Americans each year and 1.3 million people worldwide, while firearms kill about 32,000 Americans each year and "several hundred thousand" people worldwide.
100 million people were killed by tobacco in the 20th century. This is more than the death toll from World War 1 (17 million) and World War 2 (50 to 70 million) combined.
From a strictly utilitarian perspective, would there be anything to be gained by, say, starting a campaign of assassination against executives of tobacco companies?