Not nearly as sketchy as the reporting on it. I've seen too many newspaper articles treating claims that strictly heterosexual men have more sexual partners on average than strictly heterosexual women on average seriously, to take -any- reporting on the matter seriously. (Hint for those puzzling about what's wrong with this: The two numbers have to match. ETA: As Luke_A_Somers points out, the numbers don't have to be identical, and within particular subsets of the population it's possible for large disparities.)
One other case where the numbers may not match: differences in age.
For example imagine a population where everybody lives for 60 years, men always marry at 40 where they have sex once, and women marry at 20 where they also have sex once (assume they always have twins). Women over 20 will have had on average one partner, and men over 20 will have had 0.5.
So, the numbers don't need to match if you have more pairings where the man is older than the woman than the other way around (which seems to be the case); I expect that to account for some of the differenc...
From The New York Times:
So how sketchy is the research on human sexual behavior, anyway?