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Qiaochu_Yuan comments on [Link] Power of Suggestion - Less Wrong Discussion
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This isn't a completely unreasonable thing to do. For one thing, you have much more knowledge about the methodology of experiments conducted in your lab.
You also know your own results aren't fraudulent.
You know that you, personally, are not being deliberately, knowingly fraudulent. That says nothing about your assistants, nor the possibility of subconscious biases ("I really want this to be true" and "I KNOW this is true, I just have to prove it to those fools at the academy!" and "Who has the last laugh NOW Mr. Bond?!")