Robin Hanson thinks an optimal donation policy looks like saving up and investing as much money as you can and then making a large donation at the end of your life. So retirement accounts seem sensible from this point of view ("tax advantaged" seems like an important keyword here).

From a tax perspective, my understanding is that you can deduct up to 50% of your income from your taxes if you give it to charity. Are retirement account tax incentives that good? If not, you might want to put your money in a donor-advised fund instead of a retirement account. (See this comment for more relatively clueless speculation from me.)