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gwern comments on [LINK] Soylent crowdfunding - Less Wrong Discussion
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While this is true, I would expect that for many people, the main risk in Soylent would be one of overdosing on something rather than acquiring a deficiency. Soylent at least tries to provide everything that you need, while many people (me included) optimize their normal diet mainly based on criteria like cost and ease of preparation rather than healthiness. And even if we did optimize it for healthiness, your argument is essentially saying that we might very well screw up and acquire deficiencies even if we tried to ensure that we got everything that we needed.... and that argument can be applied to normal diets just as well as Soylent.
So anyone who uses the "there are lots of subtle ways of acquiring nutrition deficiencies and we might not know everything that one needs" argument against Soylent would first need to show why normal diets would avoid that argument any better.
I disagree. A random basket of foods, while likely deficient in something or other, will also likely change what it's deficient in over time, while Soylent by definition will be consistently deficient. Even if regular food vs Soylent were both equally harmful, the harm from the regular food may be less due to the variability of it. Statistics analogy borrowing from Jaynes: total error in an sampling estimate can be broken down as random error vs systematic error/bias - but random errors gradually cancel out as the sample size increases, while systematic errors remain the same. Soylent is all systematic error.
Hmm. I'll grant that.