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Vladimir_Golovin comments on Open Thread, June 2-15, 2013 - Less Wrong Discussion

5 Post author: TimS 02 June 2013 02:22AM

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Comment author: Vladimir_Golovin 05 June 2013 06:15:48AM *  2 points [-]

Here's the closest one I could find: Specificity of the neuroendocrine response to orgasm during sexual arousal in men. Also, Wikipedia article on oxytocin says that "The relationship between oxytocin and human sexual response is unclear" and cites multiple studies on oxytocin and orgasm, but none of them seem to show any major effect.

So my impression is that oxytocin secretion per se is not heavily affected by orgasm (there is a short-term rise, but that's about it.) However, orgasm significantly affects two other hormones, dopamine and prolactin (also shown in the study I linked above). After an orgasm, dopamine drops and prolactin rises and keeps surging, supposedly for about two weeks (which seems established, but I don't have a source handy.)

Here's a study that shows that prolactin rises after an orgasm in men and women but sex without orgasm doesn't affect prolactin levels: Orgasm-induced prolactin secretion: feedback control of sexual drive?:

This series of studies clearly demonstrated that plasma prolactin (PRL) concentrations are substantially increased for over 1h following orgasm (masturbation and coitus conditions) in both men and women, but unchanged following sexual arousal without orgasm.

My current crude thinking is as follows:

  1. Orgasm leads to low dopamine and high prolactin (oxytocin release is negligible).
  2. Low dopamine means low motivation (is the Coolidge effect a hard-coded exception?).
  3. High prolactin means satiation.
  4. When confronting an ugh field, one needs oxytocin and dopamine, but not prolactin.
  5. Therefore it's better to avoid the post-orgasmic dopamine and prolactin changes.
Comment author: MixedNuts 05 June 2013 11:38:12AM 0 points [-]

Thanks!

Moving back from the biological basis to the introspective level, I'd expect the high-prolactin afterglow state to reduce anxiety enough to compensate for decreased motivation. (This might be related to whether one gets wired up or sleepy after sex, which has surprisingly large individual variation.) Easy enough to set up a randomised trial.

Comment author: Vladimir_Golovin 06 June 2013 06:20:47AM *  0 points [-]

high-prolactin afterglow

You probably meant high-oxytocin afterglow.

Comment author: MixedNuts 06 June 2013 10:36:36AM 0 points [-]

No. High oxytocin is present whether you orgasm or not, as we just established. I expect this to help productivity. I also expect that orgasm would

  • Hurt productivity, because "so sleepy and satisfied, why do anything?" (from low dopamine, possibly from high prolactin)
  • Help productivity, because "feeling so relaxed, doing things that normally make me so anxious and icky is so easy right now" (from high prolactin; sex without orgasm (high-oxytocin, low-prolactin) does provide some pleasant feelings but not this specific effect)
  • Help productivity overall, relative to sex without orgasm