What sort of neurochemical hack? Gwern's page on nicotine suggests it could be used to reward certain behaviors, thus perhaps breaking down ugh fields. I haven't tried that yet (I only read that a few days ago) but I've had a great deal of success using nicotine (specifically snus) to break down my general acedia and aversion to activity.
I meant the hack I outlined in the original post: increasing oxytocin via bonding behaviors to dampen amygdala's fear response.
If it's worth saying, but not worth its own post (even in Discussion), then it goes here.