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khafra comments on Harry Potter and the Methods of Rationality discussion thread, part 24, chapter 95 - Less Wrong Discussion

6 Post author: palladias 18 July 2013 02:23AM

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Comment author: khafra 18 July 2013 01:36:33PM 8 points [-]

An excess of oxygen doesn't really help out your brain under ordinary conditions. Try hyperventilating

Hyperventilation's primary effect is to reduce CO2 levels in your blood, although it also increases oxygen. Decreasing CO2 beyond normal levels makes blood bicarbonate combine with hydrogen ions to form more CO2, which increases blood alkalinity, which makes blood vessels constrict and reduce blood supply to the brain, which makes you lightheaded. So hyperventilation is low-quality evidence about the effects of extra oxygen on your brain.

...Now I kinda want to put Gwern into a hyperbaric chamber and have him record his dual-n-back and math performance for comparison.

Comment author: gwern 18 July 2013 04:24:43PM 8 points [-]

...Now I kinda want to put Gwern into a hyperbaric chamber and have him record his dual-n-back and math performance for comparison.

I don't think that's necessary. Besides oxygen being poisonous and dangerous, it's been studied before, and it seems to be less oxygen that matters after a point than carbon dioxide. This was discussed somewhere on Greg Cochrane's blog.

Comment author: XFrequentist 18 July 2013 02:23:08PM 6 points [-]

Yup. Was about to make a similar comment. Hyperventillation will not hyper-oxygenate the brain.

That said, the "hyper-oxygenated brain -> brain function" hypothesis has been raised to the level of our attention for a very bad reason. We should let it die.

Comment author: kilobug 18 July 2013 03:08:55PM 0 points [-]

Hum, in my own experience, going down to the sea level after spending time in high altitude does a similar dizziness than hyperventilating, I always assumed it was hyper-oxygenated brain in both cases. Any explanation for the "reverse altitude sickness" ? Placebo effect (well, nocebo effect) ?