Nisan comments on Mistakes repository - Less Wrong Discussion
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Starting university with chemistry rather than computer science. Started on chemistry because I'd really enjoyed it at school, because my teacher was fantastic; realised I didn't actually like it at all. If I'd started on comp sci (and this was in 1985), I'd have done well, I'd have had much more money earlier, and my ridiculously intensive personal hobbies wouldn't have been affected.
tl;dr unexpectedly hazardous: good teachers.
Was that outcome predictable in advance?
Not at that stage, but it was definitely a mistake.