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CellBioGuy comments on Open Thread, September 23-29, 2013 - Less Wrong Discussion
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A city of ~200,000 people if you include the outlying rural areas, in which you can go from the several block wide downtown to farmland in 4-5 miles in the proper directions. Fifteen minutes from another city of 60,000 which is very much a state college town. Forty minutes away from a city of nearly 500,000 people.
Granted the city of ~200,000 has a major university and a number of biotech companies.