Depression can be irrational--chemical imbalances, not enough sunlight/exercise/etc--and can also be totally rational (life actually does suck titanium balls). Psychiatric care can help the former; the latter seems as it should be vulnerable to rationality superpowers, but either that's incorrect or I'm just not superclever enough to win. It does not help when the two coincide (sucky life situation causing serious chemical problems).
There's also the question of whether or not a terrible situation is one that makes psychiatric help readily available (I'd hope online psychiatry could help with this, but I don't really know).
and can also be totally rational (life actually does suck titanium balls)
It's a mistake to assign truth values to emotions. They can't be correct or incorrect, they can be only helpful or unhelpful. And I don't think depression is ever helpful, barring convoluted thought experiments.
If it's worth saying, but not worth its own post (even in Discussion), then it goes here.