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DanielLC comments on Open Thread, November 1 - 7, 2013 - Less Wrong Discussion
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As I said, 2 is already here, and it's becoming more here gradually.
For 3, we have a proof of concept to rip of: biological cells. Those also happens to have a specialized assembler in them already; the ribosome. And we can print instructions for it already. There's only 1 problem left and that's the protein folding problem. The protein folding problem is somewhat rapidly made progress on software wise, and even if that were to fail it won't be all that long before we ca simply brute force it with computing power. Now, the other kinds of nanobots are less clear.
The assembler (1) is trickier; however, Drexler already sorta made a blueprint for one I think, and 3 will help a great deal with it as well.
For the fooming, it's the 3 one, and ways to use it. As I said we already have the hardware, and things like the protein folding problem is exactly what an AI would be great at. Once it's solved that it has full control over biology and can essentially make The Thing and/or a literal mind control virus, and take over that way.
I'm not sure protein folding can be brute forced without quantum computers. There's too many ways for it to fold. In real life, I'm pretty sure quantum tunneling gets involved. Simulations have worked, but I there's a limit to that.