I think that you can learn a lot via empirical measurement without needing to understand underlying biochemistry. Apart from direct measurement it also about developing better metrics for things like lung function, That partly why I invested significant effort into Quantified Self community building.
Exploring the phenomenological aspect of illnesses provides an area with a lot of untapped potential for knowledge gathering.
I think there are large returns found in studying human movement in detail. As it stands a method like Feldenkrais isn't has some studies to support it but no strong scientifically investigated base. It should be possible to use cameras and computers to get accurate models of human movement and investigate an approach like Feldenkrais in deeper scientific way.
Relaxation is generally poorly understood. I think most patients could benefit from spending hours in floating tanks after having a major operation, yet few hospitals have floating tanks or maximize the relaxation in other ways. In general hospital beds and hospital food doesn't seem to be optimized for health outcomes.
Having a well developed theory that can predict placebo effects accurately would be good. On the one hand it will make it easier to gather knowledge, on the other hand it will help doctors to frame their interactions in a way that helps patients.
Having good empathy training for doctors has potential to improve healthcare.
Psychological interventions like hypnosis.
Biofeedback.
That's just a list of possibilities I can think of. There are probably things that are unknown unknowns for me.
Those approaches risk turning therapy into stabs in the dark by neglecting the details of what is actually going on inside the black box.
The 'Irrationality Game' posts in discussion came before my time here, but I had a very good time reading the bits written in the comments section. I also had a number of thoughts I would've liked to post and get feedback on, but I knew that being buried in such old threads not much would come of it. So I asked around and feedback from people has suggested that they would be open to a reboot!
I hereby again quote the original rules:
I would suggest placing *related* propositions in the same comment, but wildly different ones might deserve separate comments for keeping threads separate.
Make sure you put "Irrationality Game" as the first two words of a post containing a proposition to be voted upon in the game's format.
Here we go!
EDIT: It was pointed out in the meta-thread below that this could be done with polls rather than karma so as to discourage playing-to-win and getting around the hiding of downvoted comments. If anyone resurrects this game in the future, please do so under that system If you wish to test a poll format in this thread feel free to do so, but continue voting as normal for those that are not in poll format.