I have my suspicions about the second point: "Can be done by people who aren't subject matter experts." The whole concept of doing research projects in areas about which one knows little doesn't strike me as a good idea. GIGO is a real problem not solvable by fancy number manipulations.
I do like cross-disciplinary raids and excursions, but they involve bringing the tools, techniques, and insights of one discipline to another field and not just amateurs breezing in.
"Can be done by people who aren't subject matter experts."
I have in mind the people organizing what subject matter experts have written.
The research projects that I'm interested in here are projects that:
Some examples:
What are some other examples of topics for which research of this type could have high impact?
Note: I formerly worked as a research analyst at GiveWell and have done contract work for 80000 Hours and MIRI.