Lumifer comments on Thermodynamics of Intelligence and Cognitive Enhancement - Less Wrong Discussion
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Hypothyroidism obviously has a lot more consequences than just decreased cellular energy production and as to the metabolic syndrome, I'm not sure I'd call it a "disease of decreased cellular energy production" at all, it looks much more like a breakdown of some regulatory systems to me.
Of course, there are many ways to harm brain (=reduce intelligence) which do not involve limiting ATP in the cells.