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Lumifer comments on Thermodynamics of Intelligence and Cognitive Enhancement - Less Wrong Discussion

8 Post author: CasioTheSane 03 April 2014 11:17PM

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Comment author: Lumifer 04 April 2014 05:28:29PM 1 point [-]

There can be damage or defects in the mitochondria that inhibit it's ability to respond to hormones, for example per-oxidation of cardiolipin. Cells don't always die when they have a mitochondrial defect.

Sure, but what's the prevalence of this kind of problems? Sugar and/or glucose can cause problems in a significant chunk of population, maybe even the majority. Are you saying all these people have damaged mitochondria?

Comment author: CasioTheSane 04 April 2014 05:39:45PM 1 point [-]

I need to learn more about this, I don't have a strong belief. If I understand correctly, this is basically the idea behind the free radical theory of aging (FRTA). One interesting variant of that idea is in the article I linked above, which suggests that the focus should be on "mitochondrial membrane peroxidizability index" rather than antioxidant activity or free radical production.

It seems weird that sugar seems to cause problems in certain populations of people, but not others.

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