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private_messaging comments on Depression's evolutionary roots - Less Wrong Discussion
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Well, I haven't really thought about it, but what first comes to mind when thinking of prehistoric humans vs modern people, is that they were "tough" because their life was very hard, and we're quite "wimpy" because our lives aren't. The worst that can happen to modern people, and the worst that can happen to cavemen, are pretty much the same thing, but our overall lives are far easier and so there's much more contrast.
Perhaps it is a neurological response that causes debilitating disorder to modern people, but which merely made cavemen a little wary of going outside for non-essentials.
This seems like it should be testable. There may be no cavemen around, but there are still uncontacted and recently-contacted tribes, as well as whole countries where life is far harder than ours. I wonder what the statistics look like for those..