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satt comments on [Question] Adoption and twin studies confounders - Less Wrong Discussion

4 Post author: Stuart_Armstrong 11 July 2014 04:44PM

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Comment author: satt 14 July 2014 01:21:35AM *  3 points [-]

Since I have very little expertise in these areas, I was just wondering if anyone knew about efforts to estimate the impact of these confounders and adjust for them.

One way to assess the confounders' impact is to estimate heritability using a method that doesn't rely on making assumptions about adoptees or twins, and see whether it gives higher/lower results. Here's a paper that did so to estimate height's heritability in a sample of 3,375 sibling pairs:

I'd personally delete the first two words from that paper's title, but it nonetheless avoided whatever issues there might be with using adoptees & twins, getting a heritability estimate of 80% (with a 95% confidence interval of 46% to 85%), broadly comparable to those from older twin studies.

Comment author: Stuart_Armstrong 14 July 2014 09:26:17AM 1 point [-]

Thanks! I still think they're overconfident at having solved the problem, but it's a useful piece of the puzzle.