A mentor of mine once told me that replication is useful, but not the most useful thing you could be doing because it's often better to do a followup experiment that rests on the premises established by the initial experiment. If the first experiment was wrong, the second experiment will end up wrong too. Science should not go even slower than it already does - just update and move on, don't obsess.

If you're concerned about the velocity of scientific progress, you should also be concerned about wrong turns. A Type 1 Error (establishing a wrong result by incorrectly rejecting a null hypothesis) is, IMHO, far more damaging to science than failure to establish a correct result - possibly due to an insufficient experimental setup.