Antiochus comments on Three questions about source code uncertainty - Less Wrong Discussion
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You could think of software as being any element that is programmable - ie, even a physical plugboard can be thought of as software even though it's not typically the format we store it on.
You could think of a plugboard as hardware, too, hence there is no longer a clean hardware/software distinction
What I'm getting at is that it doesn't matter if the software is expressed in electron arrangement or plugs or neurons, if it's computable. I don't see any trouble here distinguishing between connectome and neuron.
What I am saying is that ifnyiu can't separate software from hardware, you are dealing with software in a reifiable sense.
Hardware is never computable, in the sense that simulated planes don't fly.