And what's their evidence that 23andme is selling snake oil?
From the FDA perspective 23andme has the burden of proof.
From my perspective: If SNP based genetic testing produces useful risk diagnoses that the diagnosis of different SNP based genetic testing companies should agree. As far as I know those people who used multiple of those services get different results from each one.
If you get completely different answer based on the company that you ask about your risk, do you really think that's no issue?
The results aren't "random", they're based on different information.
They are both based on the DNA and there are both based on the published literature. We aren't even sure whether all the published literature is true.
Not by me. If they disappeared into a black hole tomorrow, I would sing "Yippie! Yippie! Yippie!"
A lot of drugs fail in stage 4 trials. Would you really want to have all those drugs on the market?
From the FDA perspective 23andme has the burden of proof.
It's nice to have the guns.
If you get completely different answer based on the company that you ask about your risk, do you really think that's no issue?
Discrepant diagnoses are hardly a new issue in medicine.
I'd note that the article you referred to is almost 5 years old now. How much more data does 23andMe have to make accurate predictions? A good order of magnitude at least.
How much more will they have next year? Not so much more, as our benevolent protectors have stopped their data colle...
This is prompted by Scott's excellent article, Meditations on Moloch.
I might caricature (grossly unfairly) his post like this: