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satt comments on Open thread, August 4 - 10, 2014 - Less Wrong Discussion

5 Post author: polymathwannabe 04 August 2014 12:20PM

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Comment author: niceguyanon 08 August 2014 01:50:56PM 4 points [-]

Non-conventional thinking here, feel free to tell me why this is wrong/stupid/dangerous.

I am young and healthy, and when I catch a cold, I think " cool, when I recover immune system +1." I take this one step further though, when I don't get sick for a long time, I start to hope I get sick because I want to exercise my immune system. I know this might sound obviously wrong but can we just discuss why exactly?

My priors tell me that actively avoiding any germs and people to prevent getting sick is unhealthy. So I have lived my life not avoiding germs but also not asking people to cough on me either. But is there room to optimize? I caught something pretty nasty that lasted a month, and I am sure I got it from being at a large music festival breathing hot breathy air, but better now than catching that strain of what ever it was, when I am 70 right? And I don't mean I want to catch a serious case of pneumonia and potentially die, I mean what if there was a way to catch a strain of the common cold every now and then deliberately.

Comment author: satt 09 August 2014 02:51:28PM 1 point [-]

The catch I'd expect here is for the marginal immunological benefit from an extra cold to be less than the marginal cost of suffering an extra cold, although a priori I'm not sure which way a cost-benefit analysis would go.

It'd depend on how well colds help your immune system fight other diseases; the expected marginal number of colds prevented per extra cold suffered; the risk of longer-term side effects of colds; how the cost of getting sick changes with age (which you mentioned); the chance that you'll mistakenly catch something else (like influenza) if you try to catch someone else's cold; and the doloric cost of suffering through a cold. One might have to trawl through epidemiology papers to put usable numbers on these.

Consuming probiotics (or even specks of dirt picked up from the ground) might be easier & safer.