As an experienced writer and someone who has experience in TV and Film I can say that this concept would really work especially if you had a different scenario each episode and then also had a cast of characters who represented different spectrums of rational living. So for example:

Character A: Biohacker Character B: Quantified Self Character C: Time efficiency expert

and so on, find someone who has taken up a particular area of rationalist living and then create your scenarios:

Ergonomics (I love my Vibrams please and thank you!) Quantified Self Time Efficiency Consciousness Bio-showering Sleep cycles Religion/atheist

Then each week you would have your characters explore each area from their unique perspective and watch the fun. The test would be not only to highlight the different way that people live but also what they decide to adopt as apart of their rationalist thinking. You could take the characters to different experts that would teach them how to live in that manner and then give them a challenge. So for example:

Week 1: Bio-showers Characters go to a bio-shower expert and learn to bio shower. Characters then live 3 days on only bio-showering after extreme physical activity, sedentary activity, and medium intensity activity and after bio-showering then going to close quarters environments like a library, a subway/bus, or a store. Then track the reactions of people and how it all works out.

You could also find out how far the characters are willing to go to live a fully rational life. Cut in some personal interviews and you have a show. I would recommend 6 characters with 3 men and 3 women.

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