Wouldn't cognitive science or neuroscience be sufficient to falsify such a theory? All we really have to do is show that "good life", as seen from the inside, does not correspond to maximized happy-juice or dopamine-reward.
The most that would show is what humans tend to prefer, not what they should prefer.
As per a recent comment this thread is meant to voice contrarian opinions, that is anything this community tends not to agree with. Thus I ask you to post your contrarian views and upvote anything you do not agree with based on personal beliefs. Spam and trolling still needs to be downvoted.