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eli_sennesh comments on What are your contrarian views? - Less Wrong Discussion
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You're going to have to explain what meta-ethical view you hold such that "prefer on reflection given full knowledge and rationality" and "should prefer" are different.
I don't think neuroscience would tell you what you'd prefer on reflection given full knowledge and rationality.
Sufficiently advanced cognitive science definitely will, though.
I'm skeptical of that.