Uploads/ems are a bit of a different case.
How? Why does it matter in what substrate the information pattern called you resides in this case? I doubt the meat brain will have any connectibility issues once we have uploads.
Why does it matter in what substrate the information pattern called you resides in this case?
I am not an information pattern having, for example, a considerable somatic component :-D
If it's worth saying, but not worth its own post (even in Discussion), then it goes here.
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