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Dahlen comments on Group Rationality Diary, October 1-15 - Less Wrong Discussion
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Curcumin, 1g a day. There have been studies which compared its effect to Prozac and concluded that the effect was strong enough for it to work as an antidepressant. Apparently it's safe up to a dosage of 12g, plus it's said to have several other health benefits. As well as that, it's a reversible MAO-I, which (as far as I could understand from researching the matter) makes it fairly easy to correct imbalances in case the effect is too strong.
It's also recommended to cancer patients, which are supposed to take a much higher dosage than I do (the highest I've seen is 8g), and can do so safely.
Interesting. Did you know that curcumin is normally largely metabolized by the liver (first-pass-effect) and this can be reduced with peperin (black peper).
http://de.wikipedia.org/wiki/Curcumin
Yes. The supplements I take do contain some dose of black pepper extract, but just to be sure I always take them with a dash of pepper.