Consider a good programmer-altruist making I=150K
I think given the same skill level the programmer-altruist making 150K while living in Silicon Valley might very well make 20K less living in Germany, Japan or Singapore.
I don't know what opportunities in Europe or Asia look like, but here on the US West Coast, you can expect a salary hit of $20K or more if you're a programmer and you move from the Silicon Valley even to a lesser tech hub like Portland. Of course, cost of living will also be a lot lower.
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