Too depressed to remember to take depression medication... I know those feels. I know them well. Curcumin does not have that pesky 6-weeks-till effects problem does it? Shoring up the medication for a rainy day may be counterproductive if you'll have to sacrifice some weeks worth of pills to start up a baseline level again.

Melatonin made me wake up early, tired, and irritable. The pills available in the store are usually too much--mine were 3mg, a bit too big to even break apart usefully--and it took me a while to realize the dosage was the problem. I use it nowadays at whim to get vivid dreams.