I think "you can't condition yourself" is pretty different from "intrinsic motivation is fixed".
Ozzy was used as an example in his essay. If you ask me, Ozzy is fascinated by gender because Ozzy is of atypical gender. Gender Studies majors are often gender atypical themselves, and I think it's fairly obvious that this something borne out of life experience.
I'm sure some things are fixed, but there are environmental features here that can be hacked. Ozzy might be physically predisposed to interest in a broad thing like "people's feelings" or something, but there is some sort of psychodynamic process routing this to gender specifically.
I think the right question to ask is "what is that process, and why is it so hard to trigger on purpose?".
Most of this post is background and context, so I've included a tl;dr horizontal rule near the bottom where you can skip everything else if you so choose. :)
Here's a short anecdote of Feynman's:
There are things that I have fun doing, and there are things that I feel I have substantially more fun doing. The things in the latter group are things I generally consider a waste of time. I will focus on one specifically, because it's by far the biggest offender, and what spurred this question. Video games.
I have a knack for video games. I've played them since I was very young. I can pick one up and just be good at it right off the bat. Many of my fondest memories take place in various games played with friends or by myself and I can spend hours just reading about them. (Just recently, I started getting into fighting games technically; I plan to build my own joystick in a couple of weeks. I'm having a blast just doing the associated research.)
Usually, I'd rather play a good game than anything else. I find that the most fun I have is time spent mastering a game, learning its ins and outs, and eventually winning. I have great fun solving a good problem, or making a subtle, surprising connection—but it just doesn't do it for me like a game does.
But I want to have as much fun doing something else. I admire mathematics and physics on a very deep level, and feel a profound sense of awe when I come into contact with new knowledge regarding these fields. The other day, I made a connection between pretty basic group theory and something we were learning about in quantum (nothing amazing; it's something well known to... not undergraduates) and that was awesome. But still, I think I would have preferred to play 50 rounds of Skullgirls and test out a new combo.
TL;DR BAR
I want to have as much fun doing the things that I, on a deep level, want to do—as opposed to the things which I actually have more fun doing. I'm (obviously) not Feynman, but I want to play with ideas and structures and numbers like I do with video games. I want the same creativity to apply. The same fervor. The same want. It's not that it isn't there; I am not just arbitrarily applying this want to mathematics. I can feel it's there—it's just overshadowed by what's already there for video games.
How does one go about switching something they find immensely fun, something they're even passionate about, with something else? I don't want to be as passionate about video games as I am. I'd rather feel this way about something... else. I'd rather be able to happily spend hours reading up on [something] instead of what type of button I'm going to use in my fantasy joystick, or the most effective way to cross-up your opponent.
What would you folks do? I consider this somewhat of a mind-hacking question.