Andy_McKenzie comments on Request for suggestions: ageing and data-mining - Less Wrong Discussion
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Quite possibly, see the work of Maria Konovalenko in this area. However, this is not an easy path and is far, far more dependent on technology to safely introduce genes to cells within tissues in the body than knowledge of which genes to target. Consider that there are many diseases for which the causative genes have been known for some time, yet this has not yet been used successfully for almost all of them.
That technology pretty much exists already, its just extremely under-advertised for various reasons.