Yeah, I've had people complain about the standard basilisk and weird AI speculation stuff. Also the association with neoreactionaries, sexists and HBD people.
Sometimes you get the opposite - LW seen as an SJW forum because Scott Alexander is okay with referring to his partner as ze/zir/zur in his blog and if you are not American, or over 40, or at any rate did not go to a US college in the last 15 years this comes accross as weird. I remember even on Reddit as late as 2009 the "in" "progressive" thing was to hate Bush, not to understand something about transgenderism or feminism or what, so it is a very recent thing, I would say, in mainstream circles.
Several weeks ago I wrote a heavily upvoted post called Don't Be Afraid of Asking Personally Important Questions on LessWrong. I thought it would only be due diligence if I tried to track users on LessWrong who have received advice on this site and it's backfired. In other words, to avoid bias in the record, we might notice what LessWrong as a community is bad at giving advice about. So, I'm seeking feedback. If you have anecdotes or data of how a plan or advice directly from LessWrong backfired, failed, or didn't lead to satisfaction, please share below.