For example, what would be inappropriately off topic to post to LessWrong discussion about?
I couldn't find an answer in the FAQ. (Perhaps it'd be worth adding one.) The closest I could find was this:
What is Less Wrong?
Less Wrong is an online community for discussion of rationality. Topics of interest include decision theory, philosophy, self-improvement, cognitive science, psychology, artificial intelligence, game theory, metamathematics, logic, evolutionary psychology, economics, and the far future.
However "rationality" can be interpreted broadly enough that rational discussion of anything would count, and my experience reading LW is compatible with this interpretation being applied by posters. Indeed my experience seems to suggest that practically everything is on topic; political discussion of certain sorts is frowned upon, but not due to being off topic. People often post about things far removed from the topics of interest. And some of these topics are very broad: it seems that a lot of material about self-improvement is acceptable, for instance.
I'm a new user on lesswrong. I entered into a discussion on the bias in the medical literature where I happen to have studied the literature in some detail, and knew some facts about the bias I could add, and could demonstrate. Now the subject there happened to be vaccines, which is apparently one where some of the patrons are caught up in the crowd think, so when I pointed out politely that reality was different than their crowd think, I promptly got a -4 karma score, preventing me from posting.
I point this out because it appears that the Less Wrong system itself contains systematic flaws that tend to reinforce crowd think dynamics, rather than piercing through them. I think crowd think is the largest cause of irrationality in the world by far.
Added later: Note I have linked and commented further here: http://whyarethingsthisway.com/2015/01/15/more-wrong-by-calculated-effort/
I just looked at those posts from that discussion, and your description of the literature is clearly cherry-picked. You're only concentrating on the studies which favor your argument and not contrasting them with the studies which oppose your argument. You only acknowledge that those other studies exist in passing. By going into great detail on your preferred studies instead of presenting a comprehensive overview you're exposing yourself to sampling bias.