polymathwannabe comments on Harry Potter and the Methods of Rationality discussion thread, February 2015, chapter 104 - Less Wrong Discussion
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If the Philosopher's Stone can make transfigurations permanent, must we assume this is how Lily made Petunia permanently pretty? So Lily had access to it? So she had occasion to do some other stuff with it?
Not necessarily. Dumbledore implies that Lily used a potion, and potions may not need the Philosopher's Stone for their effects to be permanent. (Harry thinks it's the Thestral blood, and guesses that Thestral blood is also responsible for the permanency of his Cloak's magic.)
Not quite.
Some chapters later:
These are the only two mentions of Thestral blood in the story. They don't make it sound likely that Lily went on to use Thestral blood in the potion, and Harry doesn't make that connection either. The association Harry does make seems to be between Thestrals and Death and possibly invisibility, not permanency.
Well, note that Petunia did get sick for weeks, and it's only maybe die. I think it's the best fit of the things we've seen in the story, but too much remains unseen to be confident.
Hmm. Point taken. (Although the point that potion != transfiguration still holds.)
Petunia was made pretty by a potion that made her ill for an extended period, which doesn't sound like the Philosopher's Stone. Interesting theory, but I lean towards it being false.
If I remember correctly, in the canon first book the Stone is meant to be used to make a potion.
Yes, it's used to make the Elixir of Life.
I don't have HP&PS on hand, but if true, that'd be evidence for your theory. That said, while Transfiguration sickness is canonical, it seems that the whole point of the Philosopher's Stone is to bypass concerns like that, so I still lean against it being true.