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MrMind comments on Does hormetism work? Opponent process theory. - Less Wrong Discussion
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In general we should acknowledge that long and short term responses to stimulus are not linear. That they are not linear in magnitude we already knew, the article suggests they are not linear even in the 'utilons' generated.
I would though be wary that this is a general case. It's a good thing to investigate if and where a stimulus/reponse chain is linear, it's a bad thing to presuppose that's never the case.