Lumifer comments on Does hormetism work? Opponent process theory. - Less Wrong Discussion
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I would find it difficult to optimize in the short-term for mood due to noise and confounders, and pretty much impossible to optimize for immune strength since I have no easy way to measure it.
In my experience ramps are not needed at all, so I would expect that even for people who would like one it would take time on the order of a couple of weeks which is way too short to optimize for something that you can't easily measure directly.