It's not entirely clear how Hermione's troll/unicorn stuff interacts with the depletion of life-force necessary to fuel the Patronus. That said, she has a Horcrux, so at the end of the day it doesn't really matter. And if Harry can eventually destroy Azkaban, Hermione certainly can.
I'm skeptical. If dementors really do destroy your soul then having a horcrux may not be helpful against them. I'm a fan of taking V's wand down to the pit, in fact.
This is a new thread to discuss Eliezer Yudkowsky’s Harry Potter and the Methods of Rationality and anything related to it. This thread is intended for discussing chapter 116.
There is a site dedicated to the story at hpmor.com, which is now the place to go to find the authors notes and all sorts of other goodies. AdeleneDawner has kept an archive of Author’s Notes. (This goes up to the notes for chapter 76, and is now not updating. The authors notes from chapter 77 onwards are on hpmor.com.)