Here are my thoughts having just read the summary above, not the whole essay yet.

They take the fundamental rules of existence and the human condition (the “existential status quo”) as a given and don’t try to change it.

This sentence confused me. I think it could be fixed with some examples of what would constitute an instance of challenging the "existential status quo" in action. The first example I was thinking of would be ending death or aging, except you've already got transhumanists in there.

Other examples might include: * mitigating existential risks * suggesting and working on civilization as a whole reaching a new level, such as colonizing other planets and solar systems. * trying to implement better design for the fundamental functions of ubiquitous institutions, such as medicine, science, or law.

Again, I'm just giving quick feedback. Hopefully you've already given more detail in essay. Other than that, your summary seems fine to me.