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Jiro comments on [Link] Death with Dignity by Scott Adams - Less Wrong Discussion
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One possibility is medical marijuana, with sufficient precautions that it stays medical. I don't know exactly what level of precautions would be optimal, but you could do a lot better than we have now.
Always try to keep in mind that precautions are not free. Precautions stop a lot of people now from getting enough pain killing medication. I have experienced this myself, for 6 hellish weeks.