My guess is that this is a comment by the same user who posted the article.
It is. The other pages I had open still had the name visible, loldrup. Having a snit because of a -1 is unusual though. As the account is gone I can't search their past postings, but I don't remember them being egregiously wrong on LessWrong.
How does using priors affect the concept of statistical significance? The scientific convention is to use a 5% threshold for significance, no matter whether the hypothesis has been given a low or a high prior probability.
If we momentarily disregard the fact that there might be general methodological issues with using statistical significance, how does the use of priors specifically affect the appropriateness of using statistical significance?