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gwern comments on New Alzheimer’s treatment fully restores memory function in mice - Less Wrong Discussion

5 Post author: Bound_up 27 May 2015 02:33AM

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Comment author: Anders_H 27 May 2015 05:21:16AM 11 points [-]

You will probably want to edit the title to add the qualifier "in mice". Results from mouse models are notorious for not generalizing to humans. That said, this looks interesting; thanks for bringing it to my attention. I definitely hope this research gets all the funding it needs, it is certainly a bet worth taking even if the chance of payoff is low.

Comment author: gwern 27 May 2015 04:53:22PM 3 points [-]

In particular, this treatment seems predicated on the amyloid hypothesis, rather than the tau hypothesis; the amyloid hypothesis has yet to yield a drug which does anything in humans, last I heard...