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Gram_Stone comments on Roadmap: Plan of Action to Prevent Human Extinction Risks - Less Wrong Discussion
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If we have 200-300 years before well proved catastrophe, this technic may work. But in 10-50 years time scale it is better to search good clever students and pay them to work on x-risks.
Embryo selection is a third alternative, the progress of which is more susceptible to policy decisions than gene therapy, and the effects of which are more immediate than selective breeding. I recommend Shulman & Bostrom (2014) for further information.