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Marlon comments on Systemic review of antidepressants vs placebo commentary - Less Wrong Discussion

0 Post author: michael_b 03 June 2015 12:40PM

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Comment author: Marlon 04 June 2015 05:41:18PM 0 points [-]

Science is not that simple, I'm not sure you can draw such conclusions.

There was/is indeed a problem in the reporting of the evidence, that diminished the effect of antidepressant in the literature. Reporting bias is an important and serious matter in science.

That does not mean however that the antidepressant effects got down to a placebo effect. It seems that Kirsch does a lot of hand-waving to put aside the treatment effect. He did the same thing in 2008.

AFAIK the literature still says antidepressants have an effect better than placebo.

Comment author: ChristianKl 04 June 2015 11:41:34PM 0 points [-]

AFAIK the literature still says antidepressants have an effect better than placebo.

Do you have specific meta analysis in mind?

Comment author: Marlon 05 June 2015 05:53:43PM 0 points [-]

Even Kirsch's paper from 2008 results in that, and it's probably one of the most (or the most) harsh paper on antidepressants.