You're looking at Less Wrong's discussion board. This includes all posts, including those that haven't been promoted to the front page yet. For more information, see About Less Wrong.

drethelin comments on Crazy Ideas Thread - Less Wrong Discussion

22 Post author: Gunnar_Zarncke 07 July 2015 09:40PM

You are viewing a comment permalink. View the original post to see all comments and the full post content.

Comments (344)

You are viewing a single comment's thread. Show more comments above.

Comment author: drethelin 08 July 2015 04:32:36AM 4 points [-]

This would at best be a temporary solution, since this was pretty much the status quo before MRSA was as big a deal as it is now. The continued presence of antibiotics will exert a selection pressure in favor of MRSA.

Comment author: Daniel_Burfoot 08 July 2015 12:49:32PM 1 point [-]

So.... we keep the factories running. Seems like a small price to pay for the continued effectiveness of antibiotics.

Comment author: drethelin 08 July 2015 11:51:50PM 1 point [-]

If your plan is to spray MRSA into the air forever I'm pretty sure that will lead to far more deaths from untreated or treated too late infections than you would be saving by making some subset of existing infections treatable.

Comment author: Daniel_Burfoot 09 July 2015 02:14:04AM *  1 point [-]

Maybe air-spraying is the wrong distribution method - possibly it would be better to just use trucks or whatever.

There is an adjustable parameter which is how many bacteria we add to the environment per unit time. That parameter controls how quickly the resistant bacteria are replaced by non-resistant bacteria. But regardless of the value, the shape of the function of resistant bacteria population vs time should be exponential decline. So if you are worried about extra infections, you can select a small value for the replacement parameter.

Say you follow a schedule where on the first of every month, you release a bunch of bacteria, increasing the total population in an area by 1%. Then over the course of the month, the population falls back down to its initial value. If you do this for many months, you will eventually cause a large impact to the population of resistant bacteria, while never increasing the aggregate number of bacteria in the environment by more than 1%.

Comment author: buybuydandavis 08 July 2015 11:56:26PM 0 points [-]

Yeah, consider it a maintenance problem.