RomeoStevens comments on I have just donated $10,000 to the Immortality Bus, which was the most rational decision of my life - Less Wrong Discussion
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I agree that SENS is likely the best place to send donations to promote longevity research.
Actually, it's a shame that longevity research doesn't get mentioned by the Effective Altruism movement very often. I'm just now casually wondering if there might be enough value in having a Givewell-like nonprofit evaluation organization focused on longevity research to justify creating such an organization. Note that Animal Charity Evaluators is an animal-based Givewell-like nonprofit evaluation organization-- which means that this sort of thing has been done before.
This having been said, Aubrey de Grey already seems incentivized to fund the most cost-effective anti-aging research first, so directly funding SENS might be everyone's best bet.
It's both a research intensive area and one that has traditionally used up weirdness points/not garnered much interest from the usual philanthropy crowd. Probably of interest once EA is significantly bigger.