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Houshalter comments on I have just donated $10,000 to the Immortality Bus, which was the most rational decision of my life - Less Wrong Discussion
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There are animals which don't appear to age. And there have even been some successful anti aging treatments applied on animals. Even simple stuff like caloric restriction might significantly increase lifespan.
My ideal method would be cloning bodies and doing brain transplants. Of course you still need to prevent damage to the brain itself, but that solves like 90% of the other problems which occur elsewhere. And it's been shown that young blood helps the brain too. At some point we might be able to grow new brain tissue as well and keep you alive Ship of Theseus style.