The issue is that crashing the mosquito population doesn't work if even a few of them survive to repopulate - the plan needs indefinite maintenance, and the mosquitoes will eventually evolve to avoid our lab-bred dud males.

I wonder if you could breed a version of the mosquito that's healthy but has an aversion to humans, make your genetic change dominant, and then release a bunch of THOSE mosquitoes. There'd be less of a fitness gap between the modified mosquitoes and the original species, so if we just kept dumping modified males every year for a decade or two, we might be able to completely drive the original human-seeking genes out of the ecosystem.