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telomerase comments on Stupid Questions August 2015 - Less Wrong Discussion
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Is it possible to tame an octopus? Could humanity over several generations tame octopuses and breed them into work animals?
Octopodes use hemocyanin... use CRISPR to take that out, lenti vector to replace with hemoglobin, and you've got a super-octopus.
Now just apply MIRI's magic formula for making friendly superintelligence, and you've got your tame octopus. Great basis for a TV show in the genre of "Lassie", "Flipper", or "Skippy the Bush Kangaroo".
"Good on ya', Cthulipper!"
Octopuses have poisonous bites, of course.... some would see that as a bad quality in a pet.